Which coastal city was the nerve center of the spice trade in the Middle Ages, nicknamed “the Queen of the Adriatic”?

Fact

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Venice was for centuries one of the main maritime and commercial powers of the Mediterranean. Its position allowed it to connect European markets to the eastern Mediterranean routes, through which spices, silks and other luxury products passed. This prosperity contributed to the artistic and architectural development of the Republic of Venice. The city is commonly nicknamed “the Queen of the Adriatic”. Dubrovnik, another important maritime city on the Adriatic, is better known by the nickname “Pearl of the Adriatic”; so it did not match the description in the question.